NAD+
A$399
NAD+
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of the human body, essential for energy metabolism, DNA repair and cellular signalling. NAD+ levels naturally decline with age. It has been studied in the context of mitochondrial function, cognitive clarity and cellular resilience. Suitability varies with health status and medications.
Strength
1000 mg
Volume
2 mL
Format
Dual-chamber pen
Administration
Subcutaneous injection
Storage
Refrigerated 2–8°C
Product code
NJ100
Overview
NAD+ is a critical coenzyme that serves as an electron carrier in cellular energy production and as a substrate for sirtuins, PARPs and other enzymes involved in DNA repair and cellular maintenance. Its decline with age has made it a focus of longevity research.
Research on NAD+ precursors (such as NMN and NR) and direct supplementation has examined effects on metabolic function, mitochondrial health and cognitive performance. Human data on direct injectable NAD+ is limited and individual responses vary.
NAD+ is supplied as a compounded injectable product following assessment and practitioner review. This is not a TGA-approved treatment for any specific indication.
Commonly considered for
Cellular energy support
Involved in the electron transport chain and mitochondrial function central to cellular energy production.
DNA repair pathways
Acts as substrate for PARP enzymes involved in DNA damage repair.
Sirtuin activation
Sirtuins — enzymes linked to longevity research — require NAD+ for their activity.
Cognitive and neurological research
Studied in the context of brain energy metabolism and neuroprotection.
How it works
Signal
NAD+ is delivered directly to tissues via subcutaneous injection, bypassing gut absorption limitations.
Response
Cells use NAD+ as a cofactor for energy production, DNA repair enzymes and longevity-associated proteins (sirtuins).
Monitoring
Blood panels and metabolic markers may be reviewed to assess response and identify any concerns requiring adjustment.
Often stacked with
Suitability, cautions and safety
Important: This information is for educational purposes only. It does not replace assessment, diagnosis or medical advice from a qualified clinician. Suitability varies by individual health history, medications and circumstances.
Existing cancer treatment
NAD+ supports cellular energy, which may have uncertain effects in the context of cancer or active treatment. Clinical review is essential.
Cardiovascular conditions
High-dose NAD+ can transiently affect heart rate in some individuals. Discuss with a clinician if you have a cardiac condition.
Pregnancy, breastfeeding or trying to conceive
Safety data is insufficient. Clinical guidance required.
Autoimmune conditions
Effects on immune cell activity require assessment in people with autoimmune conditions or immunosuppressive therapy.
Medications affecting metabolism
NAD+ interacts with various enzymatic pathways. Disclose all medications.
Answer each question honestly. If you answer Yes to any question, we recommend discussing this compound with a qualified clinician before proceeding.
Do you currently have cancer or are you undergoing cancer treatment?
Do you have a diagnosed cardiovascular or cardiac rhythm condition?
Are you pregnant, breastfeeding or trying to conceive?
Do you have an autoimmune condition or are you taking immunosuppressant medication?
Are you using other injectable compounds or significant supplement combinations?
If you have any of the following, discuss with a clinician before purchasing or using this product
- Rapid or irregular heartbeat
- Flushing, warmth or significant skin redness
- Shortness of breath
- Significant nausea
- Dizziness or lightheadedness
Adverse effects and safety signals
Common effects
Generally mild and often resolve without intervention. Monitor and report if persistent.
- Flushing or skin warmth — Common during or after administration. Usually brief.
- Nausea — Particularly at higher doses.
- Headache
- Injection-site discomfort
- Fatigue or energy fluctuation initially
Discuss promptly with a clinician
If any of the following occur, stop use and contact your prescribing practitioner.
- Persistent rapid heartbeat
- Significant or prolonged flushing
- Repeated vomiting
- Dizziness or presyncope
Seek emergency help immediately
If you experience any of the following, call emergency services (000 in Australia) immediately. These may be signs of a serious allergic reaction or medical emergency.
- Difficulty breathing
- Facial, lip or tongue swelling
- Widespread hives or rash
- Collapse or fainting
Important: Before use, tell your practitioner if you have ever had an allergic reaction to any peptide, injection product or medicine. Allergic reactions can occur even with first use. I understand that I should seek urgent medical help if I experience signs of a serious allergic reaction.
Medications and interactions
Medicines and treatments to discuss
NAD+ may interact with medications affecting cellular energy pathways, chemotherapy agents, alcohol metabolising pathways and supplements targeting similar longevity pathways (e.g. resveratrol, NMN, NR). Disclose all current treatments.
Bloodwork and monitoring
The following tests may be considered at baseline and during use. Your Zenith practitioner will advise on what is relevant for you.
Baseline (before use)
- Full blood count
- Liver function
- Fasting glucose
- Lipid profile
Administration
Administer by subcutaneous injection. Some protocols use IV administration — follow your specific protocol card.
Rotate injection sites to reduce local tissue changes.
Slow administration is recommended to minimise flushing.
Use a fresh needle for each injection and dispose of sharps safely.
Storage and handling
Store refrigerated at 2–8°C.
Once activated, use within 28 days when refrigerated.
Do not freeze.
Protect from light. NAD+ is light-sensitive.
Research context: Extensive research on NAD+ precursors and direct supplementation in ageing and metabolic studies.
Frequently asked
NAD+ is a coenzyme found in every human cell. It is essential for energy metabolism, DNA repair and the activity of longevity-related enzymes called sirtuins.
Oral NAD+ has poor bioavailability due to gut metabolism. Subcutaneous or IV administration delivers it directly into systemic circulation.
Flushing is a common and usually harmless transient effect related to NAD+ metabolism. Slower administration can reduce this.
Regulatory and classification note: Injectable NAD+ is a compounded product supplied following practitioner review. It is not TGA-approved for the indications described. This information is educational and does not constitute medical advice.
Regulatory & safety information
NAD+ is supplied subject to suitability assessment and applicable UAE regulatory requirements. Information provided is general and is not a substitute for professional medical advice, diagnosis or treatment.
Always consult a qualified healthcare professional before starting, changing or stopping any product, particularly if you are pregnant, breastfeeding, under 18, or managing a medical condition.
Why treatment isn't self-selected
Treatment decisions need context.
Selecting a treatment option is the starting point. What's clinically appropriate for you is determined by three things together.
Your bloodwork
Relevant biomarkers help identify which treatment options may be appropriate — and which should be avoided.
Your health history
Existing conditions, medications and goals are considered alongside your results, not in isolation.
Practitioner review
A licensed practitioner reviews every request before anything is approved, dosed or supplied.
Before you choose
Your bloodwork can change the conversation.
Recent bloodwork gives your practitioner more to work with — helping identify what may be appropriate, what should be avoided, and where a different option might be better suited to your results.
Already uploaded results? Your practitioner reviews them alongside any treatment request — no need to repeat information.
Optional at this stage. Required before final approval.
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Purchase
NAD+
Supplied following assessment, bloodwork and practitioner review.
Price
A$399
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